Four configurations of sexual desire were constructed to reflect what was found in this population of bisexually-active Latino men: (a) lifetime homoerotic desire and casual sex with women (b) lifetime heteroerotic desire, but commercial sex with men (c) lifetime heteroerotic/transgender desire (d) lifetime sexual desire for women and men. To achieve this aim, an analysis was made of 18 sexual histories of bisexually active Latino men who participated in a two-year ethnographic study. The goal of this article is to present a comprehensive understanding of how sexual desire is organized, enacted through sexual activity, and interpreted in the sexual lives of bisexually-active Latino men. Latino male bisexuality has been studied for the most part with a focus on men who have sex with men (MSM) and with little attention to sexual desire.